Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315007 | 0.88 | NPC1 (0.40) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8309970 | 0.83 | KDM4E (0.37) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8312015 | 0.78 | APP (0.46) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8310753 | 0.76 | ALDH1A1 (0.45) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8311214 | 0.76 | S1PR1 (0.39) | MAPTNPC1RAB9AKDM4EF2RL3 | |
| SCHEMBL8316157 | 0.76 | F2RL3 (0.37) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8314511 | 0.75 | FFAR4 (0.39) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8315191 | 0.74 | MAPK1 (0.41) | MAPTKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL8310437 | 0.74 | F2RL3 (0.35) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8311101 | 0.74 | KDM4E (0.48) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |