Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 7/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312015 | 0.81 | APP (0.46) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL8311014 | 0.74 | MAPT (0.42) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL8315007 | 0.72 | NPC1 (0.40) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL27294716 | 0.70 | ESR1 (0.49) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL8310912 | 0.67 | MIF (0.54) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL8314981 | 0.67 | ESR1 (0.44) | NPC1MAPTRAB9AESR1ESR2 | |
| SCHEMBL8311404 | 0.67 | ESR1 (0.48) | KDM4EALDH1A1LMNAGAANPC1 | |
| SCHEMBL31677643 | 0.66 | SNCA (0.50) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL8311480 | 0.66 | ESR1 (0.47) | NPC1MAPTRAB9AESR1ESR2 | |
| SCHEMBL8315342 | 0.66 | ESR1 (0.47) | KDM4EALDH1A1LMNAGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |