Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29007533 | 0.89 | FNTA (0.65) | CES2CES1FNTAFNTBCYP19A1 | |
| SCHEMBL8316648 | 0.88 | CES2 (0.52) | CES2CES1FNTAFNTBCNR2 | |
| SCHEMBL14367096 | 0.84 | MAOB (0.53) | CES2CES1FNTAFNTBALDH1A1 | |
| SCHEMBL28116754 | 0.84 | HTT (0.52) | ALDH1A1L3MBTL1GAAKMT2AMEN1 | |
| SCHEMBL5691685 | 0.82 | CES1 (0.64) | CES2CES1FNTAFNTBAKR1B1 | |
| SCHEMBL11106093 | 0.81 | KEAP1 (0.53) | ALDH1A1MAPK1KMT2AHDAC8HDAC6 | |
| SCHEMBL7693742 | 0.81 | CYP19A1 (0.49) | CES2CES1CYP19A1AKR1B1ALDH1A1 | |
| SCHEMBL538524 | 0.79 | CYP19A1 (0.76) | CES2CES1CYP19A1AKR1B1ALDH1A1 | |
| SCHEMBL339795 | 0.79 | CES1 (0.67) | CES2CES1FNTAFNTBAKR1B1 | |
| SCHEMBL58882 | 0.79 | TDP1 (0.44) | CES2CES1CYP19A1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118360265-A | Diaminopimelate dehydrogenase mutant and application thereof in D-amino acid synthesis | 华东理工大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-116200359-A | Transaminase mutant and application thereof | 迪嘉药业集团股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-116004562-A | Transaminase mutant and application thereof | 迪嘉药业集团股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2020223102-A1 | ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS | CODEXIS, INC. (US) | 2020-11-05 | — | — | WO | disclosed |
| CN-106279250-B | A kind of stannous phenide complex and its preparation method and application | 衡阳师范学院 | 2018-11-27 | — | — | CN | disclosed |
| CN-105541898-B | A kind of phenylpropionic acid benzoyl hydrazone two of 2 carbonyl 3 is to methyl-benzyl tin complex and its preparation method and application | 衡阳师范学院 | 2018-02-09 | — | — | CN | disclosed |
| CN-106279250-A | A kind of 2 carbonyl 3 phenylpropionic acid para hydroxybenzene formyl hydrazone stannous phenide coordination compounds and its preparation method and application | 衡阳师范学院 | 2017-01-04 | — | — | CN | disclosed |
| EP-0093376-B2 | 1-Sulfo-2-azetidinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0225634-B1 | Antibacterial compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-04-06 | — | — | EP | disclosed |
| EP-0234549-B1 | METHOD FOR PRODUCTION OF CEPHALOSPORIN COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 1992-12-16 | — | — | EP | disclosed |
| EP-0095764-A2 | 2-Oxoazetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-12-07 | — | — | EP | disclosed |
| US-4416817-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-11-22 | — | — | US | disclosed |
| EP-0093376-A2 | 1-Sulfo-2-azetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-09 | — | — | EP | disclosed |
| EP-0074611-A2 | Method for production of cephalosporin compounds | Takeda Chemical Industries, Ltd. (JP) | 1983-03-23 | — | — | EP | disclosed |
| EP-0053815-A1 | 2-Oxoazetidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |
| EP-0053816-A1 | 1-Sulfo-2-oxoazetidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |
| EP-0053387-A1 | Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-09 | — | — | EP | disclosed |
| EP-0050965-A1 | Beta-lactamase inhibitory composition | Takeda Chemical Industries, Ltd. (JP) | 1982-05-05 | — | — | EP | disclosed |
| EP-0021676-A1 | 3-Methoxy-2-oxoazetidine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |