Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.67 |
| ▸ | CES2 | O00748 | 2/20 | 0.67 |
| ▸ | FNTA | P49354 | 2/20 | 0.55 |
| ▸ | FNTB | P49356 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119176 | 0.82 | CES2 (0.59) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL574185 | 0.81 | CES1 (1.00) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL11044523 | 0.81 | CES1 (0.64) | CES1CES2FNTAFNTBAKR1B1 | |
| Methyl Phenylpyruvate SCHEMBL237446 | 0.81 | CES2 (0.64) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL5691685 | 0.81 | CES1 (0.64) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL14813098 | 0.81 | FNTA (0.59) | CES1CES2FNTAFNTBMEN1 | |
| SCHEMBL8767243 | 0.79 | CES1 (0.50) | CES1CES2FNTAFNTBAKR1B1 | |
| Methyl Phenylpyruvate SCHEMBL27849227 | 0.79 | CES2 (0.61) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL7636977 | 0.79 | ALDH1A1 (0.66) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL8311407 | 0.79 | CES2 (0.61) | CES1CES2FNTAFNTBAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008009-A1 | DIALYSIS AND FLUSHING SOLUTION FOR INTRAPERITONEAL ADMINISTRATION | NEPHRO-MEDICA PHARMAZEUTISCHE VERTRIEBSGESELLSCHAFT MBH (DE) | 1991-06-13 | — | — | WO | claimed |
| WO-2023075814-A1 | ENGINEERED BIOSYNTHETIC PATHWAYS FOR PRODUCTION OF P-COUMARIC ACID BY FERMENTATION | ZYMERGEN INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| CN-106417342-A | Weeding composition containing topramezone and flucarbazone-sodium | 广东中迅农科股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106305740-A | Weeding composition with topramezone and pinoxaden | 广东中迅农科股份有限公司 | 2017-01-11 | — | — | CN | disclosed |
| EP-2287292-B1 | PLANT DERIVED HYDROXY PHENYL PYRUVATE DIOXYGNEASES (HPPD) RESISTANT AGAINST TRIKETONE HERBICIDES AND TRANSGENIC PLANTS CONTAINING THESE DIOXYGENASES | SYNGENTA LTD (GB) | 2015-04-08 | — | — | EP | disclosed |
| EP-2287292-B1 | PLANT DERIVED HYDROXY PHENYL PYRUVATE DIOXYGNEASES (HPPD) RESISTANT AGAINST TRIKETONE HERBICIDES AND TRANSGENIC PLANTS CONTAINING THESE DIOXYGENASES | SYNGENTA LTD (GB) | 2015-04-08 | — | — | EP | disclosed |
| EP-2848125-A1 | Herbicidal compositions | Syngenta Limited (GB) | 2015-03-18 | — | — | EP | disclosed |
| EP-2326722-B1 | HERBICIDE TOLERANT PLANTS | SYNGENTA LTD (GB) | 2014-08-06 | — | — | EP | disclosed |
| US-8771959-B2 | Methods for the production of plants resistant to HPPD herbicides | SYNGENTA LIMITED (GB) | 2014-07-08 | — | — | US | disclosed |
| US-8735660-B2 | Methods for the production of plants resistant to HPPD herbicides | SYNGENTA LIMITED (GB) | 2014-05-27 | — | — | US | disclosed |
| US-20080146447-A1 | Methods for the production of plants resistant to HPPD herbicides | SYNGENTA LIMITED | 2008-06-19 | — | — | US | disclosed |
| US-20080076178-A1 | Methods for the production of plants resistant to HPPD herbicides | SYNGENTA LIMITED | 2008-03-27 | — | — | US | disclosed |
| US-7312379-B2 | Methods for production of plants resistant to HPPD herbicides | SYNGENTA LIMITED (GB) | 2007-12-25 | — | — | US | disclosed |
| US-20060021085-A1 | Method for producing transgenic plants having an elevated vitamin E content by modifying the serine-acetyltransferase content | SUNGENE GMBH & CO. KGAA (DE) | 2006-01-26 | — | — | US | disclosed |
| US-20040058427-A1 | Herbicide resistant plants | SYNGENTA LIMITED (GB) | 2004-03-25 | — | — | US | disclosed |
| EP-1341903-A2 | PLANT DERIVED HYDROXY PHENYL PYRUVATE DIOXYGNEASES (HPPD) RESISTANT AGAINST TRIKETONE HERBICIDES AND TRANSGENIC PLANTS CONTAINING THESE DIOXYGENASES | Syngenta Limited (GB) | 2003-09-10 | — | — | EP | disclosed |
| EP-1341903-A2 | PLANT DERIVED HYDROXY PHENYL PYRUVATE DIOXYGNEASES (HPPD) RESISTANT AGAINST TRIKETONE HERBICIDES AND TRANSGENIC PLANTS CONTAINING THESE DIOXYGENASES | Syngenta Limited (GB) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002046387-A3 | PLANT DERIVED HYDROXY PHENYL PYRUVATE DIOXYGENASES (HPPD) RESISTANT AGAINST TRIKETONE HERBICIDES AND TRANSGENIC PLANTS CONTAINING THESE DIOXYGENASES | SYNGENTA LTD (GB) | 2003-01-16 | — | — | WO | disclosed |
| WO-2002046387-A2 | PLANT DERIVED HYDROXY PHENYL PYRUVATE DIOXYGENASES (HPPD) RESISTANT AGAINST TRIKETONE HERBICIDES AND TRANSGENIC PLANTS CONTAINING THESE DIOXYGENASES | SYNGENTA LIMITED (GB) | 2002-06-13 | — | — | WO | disclosed |
| WO-2002046387-A2 | PLANT DERIVED HYDROXY PHENYL PYRUVATE DIOXYGENASES (HPPD) RESISTANT AGAINST TRIKETONE HERBICIDES AND TRANSGENIC PLANTS CONTAINING THESE DIOXYGENASES | SYNGENTA LIMITED (GB) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076178-A1 | Methods for the production of plants resistant to HPPD herbicides | PNKP, HPD, GNPDA1 | CES1 964/4885CES2 225/4885FNTA 405/4885 |
| US-20080146447-A1 | Methods for the production of plants resistant to HPPD herbicides | PNKP, HPD, GNPDA1 | CES1 964/4885CES2 225/4885FNTA 405/4885 |
| US-20040058427-A1 | Herbicide resistant plants | HPD, PEPD, DDC | CES1 748/4885CES2 1337/4885FNTA 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.