Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.60 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.60 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.60 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.60 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48440 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL19410297 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL7289584 | 0.92 | PRMT3 (0.63) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL27173945 | 0.86 | PRMT3 (0.63) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL380653 | 0.86 | — | — | |
| SCHEMBL7855146 | 0.84 | TDP1 (0.60) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL2306167 | 0.84 | PRMT3 (0.55) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Alcohol SCHEMBL28731571 | 0.84 | PRMT3 (0.55) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25212094 | 0.83 | ALDH1A1 (0.61) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL1408747 | 0.83 | ALDH1A1 (0.61) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922640-A | COMPRISING A POROUS INORGANIC CARRIER, A COMPLEX OF NITROGEN CONTAINING COMPOUND AND A COPPER HALIDE, HIGH SELECTIVITY, EASILY DESORBED, RECOVERY BY TREATING WITH A REDUCING AGENT | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0792684-A2 | Novel adsorbent for carbon monoxide and method | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1997-09-03 | — | — | EP | disclosed |