Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SLC18A1 | P54219 | 1/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14270576 | 0.84 | TAAR1 (0.36) | TSHRSLC18A1SLC18A2PLA2G1BCYP1A2 | |
| SCHEMBL16838138 | 0.83 | CYP1A2 (0.35) | TSHRSLC18A1SLC18A2HPGDPLA2G1B | |
| SCHEMBL15250773 | 0.83 | SLC18A1 (0.37) | TSHRSLC18A1SLC18A2HPGDKMT2A | |
| SCHEMBL27680833 | 0.82 | SLC18A1 (0.40) | TSHRSLC18A1SLC18A2HPGDPLA2G1B | |
| SCHEMBL16838137 | 0.82 | MAPK1 (0.37) | TSHRSLC18A1SLC18A2PLA2G1BCYP1A2 | |
| SCHEMBL15030165 | 0.80 | ALDH1A1 (0.42) | PLA2G1BCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL19290592 | 0.79 | ALDH1A1 (0.38) | TSHRHPGDPLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL16715358 | 0.77 | ADRA2C (0.55) | HPGDCYP2C9SMN1; SMN2KCNH2ALDH1A1 | |
| SCHEMBL19232759 | 0.77 | TSHR (0.35) | TSHRHPGDPLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL6724337 | 0.77 | TSHR (0.45) | TSHRHPGDSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919474-B1 | HBV INHIBITOR AND USE THEREOF | XIAN XINTONG PHARMACEUTICAL RES CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |
| EP-1944305-B1 | Quinoline derivatives as phosphodiesterase inhibitors | GLAXO GROUP LTD (GB) | 2011-10-19 | — | — | EP | disclosed |
| CN-101815710-A | Pyrimidine and pyridine derivatives, their pharmaceutical use and compositions | PFIZER | 2010-08-25 | — | — | CN | disclosed |
| EP-1633748-B1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-03-05 | — | — | EP | disclosed |
| WO-2004103998-A1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-02 | — | — | WO | disclosed |