Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1952554 | 1.00 | RECQL (0.44) | RECQLACACBTP53LMNATDP1 | |
| SCHEMBL845078 | 1.00 | RECQL (0.44) | RECQLACACBTP53LMNATDP1 | |
| SCHEMBL6288389 | 0.91 | RECQL (0.50) | RECQLLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5901288 | 0.91 | RECQL (0.50) | RECQLLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10482801 | 0.91 | RECQL (0.54) | RECQLLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23441772 | 0.91 | RECQL (0.54) | RECQLLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2792108 | 0.90 | RECQL (0.49) | RECQLLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2790670 | 0.90 | RECQL (0.49) | RECQLLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2792110 | 0.90 | RECQL (0.49) | RECQLLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5901312 | 0.90 | RECQL (0.49) | RECQLLMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4764888-B2 | — | — | 2011-09-07 | — | — | JP | claimed |
| CN-101142167-A | Compounds that stimulate glucose utilization and methods of use | UNIV ALBERTA (CA) | 2008-03-12 | — | — | CN | claimed |
| EP-1868982-A2 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | The Governors of the University of Alberta (CA) | 2007-12-26 | — | — | EP | claimed |
| WO-2006117686-A2 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2006-11-09 | — | — | WO | claimed |
| US-20060205811-A1 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2006-09-14 | — | — | US | claimed |
| US-20060173208-A1 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2006-08-03 | — | — | US | claimed |
| US-20050182133-A1 | Compounds that stimulate glucose utilization and methods of use | UNIVERSITY OF ALBERTA (CA) | 2005-08-18 | — | — | US | claimed |
| EP-1499580-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | UNIVERSITY OF ALBERTA (CA) | 2005-01-26 | — | — | EP | claimed |
| US-20040116517-A1 | Compounds that stimulate glucose utilization and methods of use | UNIVERSITY OF ALBERTA (CA) | 2004-06-17 | — | — | US | claimed |
| WO-2003082800-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE UNIVERSITY OF ALBERTA (CA) | 2003-10-09 | — | — | WO | claimed |
| US-20030191182-A1 | Compounds that stimulate glucose utilization and methods of use | GOVERNORS OF THE UNIVERSITY OF ALBERTA, THE (CA) | 2003-10-09 | — | — | US | claimed |
| EP-1868982-B1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | UNIV ALBERTA (CA) | 2015-04-29 | — | — | EP | disclosed |
| US-8202901-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-06-19 | — | — | US | disclosed |
| EP-1499580-B1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | UNIV ALBERTA (CA) | 2012-03-28 | — | — | EP | disclosed |
| US-20090258835-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA TEC EDMONTON (CA) | 2009-10-15 | — | — | US | disclosed |
| US-20050182133-A1 | Compounds that stimulate glucose utilization and methods of use | UNIVERSITY OF ALBERTA (CA) | 2005-08-18 | — | — | US | disclosed |
| EP-1499580-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | UNIVERSITY OF ALBERTA (CA) | 2005-01-26 | — | — | EP | disclosed |
| US-20040116517-A1 | Compounds that stimulate glucose utilization and methods of use | UNIVERSITY OF ALBERTA (CA) | 2004-06-17 | — | — | US | disclosed |
| WO-2003082800-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE UNIVERSITY OF ALBERTA (CA) | 2003-10-09 | — | — | WO | disclosed |
| US-20030191182-A1 | Compounds that stimulate glucose utilization and methods of use | GOVERNORS OF THE UNIVERSITY OF ALBERTA, THE (CA) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182133-A1 | Compounds that stimulate glucose utilization and methods of use | GPR119, SLC2A4, SLC2A1 | RECQL 2753/4885ACACB 662/4885TP53 4505/4885 |
| US-20090258835-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | GPR119, SLC2A4, SLC2A1 | RECQL 2753/4885ACACB 662/4885TP53 4505/4885 |
| US-20060173208-A1 | Compounds that stimulate glucose utilization and methods of use | GPR119, SLC2A4, SLC2A1 | RECQL 2676/4885ACACB 683/4885TP53 4446/4885 |
| US-20060205811-A1 | Compounds that stimulate glucose utilization and methods of use | GPR119, SLC2A4, SLC2A1 | RECQL 2676/4885ACACB 683/4885TP53 4446/4885 |
| US-20030191182-A1 | Compounds that stimulate glucose utilization and methods of use | GPR119, SLC2A3, CYCS | RECQL 4092/4885ACACB 646/4885TP53 4469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.