Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PTPRF | P10586 | 5/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314166 | 0.88 | CA12 (0.41) | FFAR1CYP26A1CYP26B1MEN1KMT2A | |
| SCHEMBL8315855 | 0.85 | RAB9A (0.48) | FFAR1CYP26A1CYP26B1MEN1KMT2A | |
| SCHEMBL8316517 | 0.83 | BCL2 (0.43) | MEN1KMT2AS1PR1ALDH1A1CA12 | |
| SCHEMBL8310165 | 0.83 | FFAR1 (0.56) | FFAR1CYP26A1CYP26B1MEN1KMT2A | |
| SCHEMBL6598772 | 0.79 | TP53 (0.45) | CYP26A1CYP26B1MEN1KMT2APTPRF | |
| SCHEMBL8311225 | 0.79 | CYP26A1 (0.42) | FFAR1CYP26A1CYP26B1MEN1KMT2A | |
| SCHEMBL8311016 | 0.79 | CYP26B1 (0.42) | FFAR1CYP26A1CYP26B1MEN1KMT2A | |
| SCHEMBL6599311 | 0.79 | ALOX5 (0.48) | FFAR1CYP26A1CYP26B1MEN1KMT2A | |
| SCHEMBL3385454 | 0.79 | CYP26A1 (0.39) | FFAR1CYP26A1CYP26B1MEN1KMT2A | |
| SCHEMBL6598856 | 0.79 | SMN1; SMN2 (0.43) | MEN1KMT2APTPRFPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |