Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 7/20 | 0.35 |
| ▸ | METAP1 | P53582 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617890 | 0.83 | ACE (0.41) | ACEL3MBTL1KMT2APOLBMETAP2 | |
| SCHEMBL3830001 | 0.83 | ACE (0.43) | ACEL3MBTL1KMT2APOLBMETAP2 | |
| SCHEMBL8305005 | 0.81 | HDAC1 (0.39) | ACEALDH1A1MAPT | |
| SCHEMBL28498823 | 0.79 | ACE (0.46) | ACEL3MBTL1KMT2APOLB | |
| SCHEMBL28498821 | 0.79 | ACE (0.46) | ACEL3MBTL1KMT2APOLB | |
| SCHEMBL13314020 | 0.76 | ACE (0.46) | ACEL3MBTL1KMT2APOLBALDH1A1 | |
| SCHEMBL300278 | 0.76 | ACE (0.49) | ACEL3MBTL1KMT2APOLB | |
| SCHEMBL4458272 | 0.76 | ACE (0.49) | ACEL3MBTL1KMT2APOLB | |
| SCHEMBL13482629 | 0.76 | ACE (0.49) | ACEL3MBTL1KMT2APOLB | |
| SCHEMBL4650239 | 0.76 | ACE (0.49) | ACEL3MBTL1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004075889-A1 | PROCESS FOR PREPARATION OF PERINDOPRIL AND SALTS THEREOF | LUPIN LIMITED (IN) | 2004-09-10 | — | — | WO | disclosed |