SCHEMBL4617890

SCHEMBL4617890

CCCC(NC(C)C(=O)OCC)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACE P12821 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.37
METAP2 P50579 7/20 0.36
METAP1 P53582 5/20 0.36
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 2/20 0.35
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3830001 0.86 ACE (0.43) ACEL3MBTL1METAP2METAP1KMT2A
SCHEMBL14261146 0.86 ACE (0.46) ACEL3MBTL1ALDH1A1LMNAHSD17B10
SCHEMBL13314020 0.86 ACE (0.46) ACEL3MBTL1ALDH1A1LMNAHSD17B10
SCHEMBL8312138 0.83 ACE (0.39) ACEL3MBTL1METAP2METAP1ALDH1A1
SCHEMBL28498821 0.82 ACE (0.46) ACEL3MBTL1LMNAKMT2APOLB
SCHEMBL28498823 0.82 ACE (0.46) ACEL3MBTL1LMNAKMT2APOLB
SCHEMBL715422 0.79 CHRM1 (0.41) ACEALDH1A1
SCHEMBL4458272 0.79 ACE (0.49) ACEL3MBTL1LMNAKMT2APOLB
SCHEMBL13482629 0.79 ACE (0.49) ACEL3MBTL1LMNAKMT2APOLB
SCHEMBL1992431 0.79 ACE (0.49) ACEL3MBTL1LMNAKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9717931-B2 Solubilization of triazine UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof L'OREAL (FR) 2017-08-01 US claimed
WO-2017101103-A1 COMPOSITION IN THE FORM OF AN OIL-IN-WATER EMULSION L'OREAL (FR) 2017-06-22 WO claimed
EP-1618927-B1 Sunscreen compositions containing a triazine filter solubilised by a mixture of an arylalkyl benzoate derivative and an amide-modified oil; uses in cosmetics OREAL (FR) 2012-08-01 EP claimed
EP-1796622-B1 COSMETIC COMPOSITIONS CONTAINING A TRIAZINE DERIVATIVE, AN AMIDE-BASED OIL AND A EUTECTIC MIXTURE OF N-BUTYL-PHTHALIMIDE/ISOPROPYLPHTHALIMIDE OREAL (FR) 2008-01-23 EP claimed
US-20070140997-A1 Photoprotective compositions containing a triazine derivative, an amide-based oil and a eutectic mixture of n-butylphthalimide/isopropylphthalimide L'OREAL (FR) 2007-06-21 US claimed
EP-1796622-A1 COSMETIC COMPOSITIONS CONTAINING A TRIAZINE DERIVATIVE, AN AMIDE-BASED OIL AND A EUTECTIC MIXTURE OF N-BUTYL-PHTHALIMIDE/ISOPROPYLPHTHALIMIDE L'OREAL (FR) 2007-06-20 EP claimed
WO-2006003028-A1 COSMETIC COMPOSITIONS CONTAINING A TRIAZINE DERIVATIVE, AN AMIDE-BASED OIL AND A EUTECTIC MIXTURE OF N-BUTYL-PHTHALIMIDE/ISOPROPYLPHTHALIMIDE L'OREAL (FR) 2006-01-12 WO claimed
US-20060002872-A1 Solubilization of triazine UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof L'OREAL (FR) 2006-01-05 US claimed
US-20060002873-A1 Photostabilization of dibenzoylmethane UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof L'OREAL (FR) 2006-01-05 US claimed
US-12121604-B2 Composition comprising hydroxylated diphenylmethane derivatives L'OREAL (FR) 2024-10-22 US disclosed
CN-117338637-A Compositions comprising hydroxylated diphenylmethane derivatives 莱雅公司 2024-01-05 CN disclosed
CN-108366934-B Composition having a colour transition during application 莱雅公司 2021-09-07 CN disclosed
US-20180303730-A1 COMPOSITION HAVING A COLOUR TRANSFORMATION DURING APPLICATION L'OREAL (FR) 2018-10-25 US disclosed
EP-3389605-A1 COMPOSITION HAVING A COLOUR TRANSFORMATION DURING APPLICATION L'Oréal (FR) 2018-10-24 EP disclosed
EP-1796622-B1 COSMETIC COMPOSITIONS CONTAINING A TRIAZINE DERIVATIVE, AN AMIDE-BASED OIL AND A EUTECTIC MIXTURE OF N-BUTYL-PHTHALIMIDE/ISOPROPYLPHTHALIMIDE OREAL (FR) 2008-01-23 EP disclosed
US-20070140997-A1 Photoprotective compositions containing a triazine derivative, an amide-based oil and a eutectic mixture of n-butylphthalimide/isopropylphthalimide L'OREAL (FR) 2007-06-21 US disclosed
EP-1796622-A1 COSMETIC COMPOSITIONS CONTAINING A TRIAZINE DERIVATIVE, AN AMIDE-BASED OIL AND A EUTECTIC MIXTURE OF N-BUTYL-PHTHALIMIDE/ISOPROPYLPHTHALIMIDE L'OREAL (FR) 2007-06-20 EP disclosed
WO-2006003028-A1 COSMETIC COMPOSITIONS CONTAINING A TRIAZINE DERIVATIVE, AN AMIDE-BASED OIL AND A EUTECTIC MIXTURE OF N-BUTYL-PHTHALIMIDE/ISOPROPYLPHTHALIMIDE L'OREAL (FR) 2006-01-12 WO disclosed
US-20060002872-A1 Solubilization of triazine UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof L'OREAL (FR) 2006-01-05 US disclosed
US-20060002873-A1 Photostabilization of dibenzoylmethane UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof L'OREAL (FR) 2006-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070140997-A1 Photoprotective compositions containing a triazine derivative, an amide-based oil and a eutectic mixture of n-butylphthalimide/isopropylphthalimide CRYZ, ERCC2, MITF ACE 3364/4885L3MBTL1 2520/4885METAP2 642/4885
US-20180303730-A1 COMPOSITION HAVING A COLOUR TRANSFORMATION DURING APPLICATION KRT18, F12, CUTA ACE 4343/4885L3MBTL1 1276/4885METAP2 3967/4885
US-20060002873-A1 Photostabilization of dibenzoylmethane UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof ARNT, AHR, CRYZ ACE 1880/4885L3MBTL1 2956/4885METAP2 3242/4885
US-12121604-B2 Composition comprising hydroxylated diphenylmethane derivatives DEGS1, ALOX5, ALOX12 ACE 4165/4885L3MBTL1 3045/4885METAP2 4318/4885
US-20060002872-A1 Solubilization of triazine UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof CRYZ, TOP2A, CUTA ACE 3223/4885L3MBTL1 4188/4885METAP2 1745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.