⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894261 | 0.79 | — | — | |
| SCHEMBL29392814 | 0.75 | — | — | |
| SCHEMBL69524 | 0.75 | — | — | |
| SCHEMBL25433140 | 0.72 | CA6 (0.62) | — | |
| SCHEMBL31122789 | 0.72 | CA6 (0.62) | — | |
| SCHEMBL29619760 | 0.72 | — | — | |
| SCHEMBL185204 | 0.72 | — | — | |
| SCHEMBL10323584 | 0.72 | — | — | |
| SCHEMBL8059885 | 0.72 | IDO1 (0.57) | — | |
| SCHEMBL29521801 | 0.70 | CA3 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098876-A1 | CARBONYL SUBSTITUTED DIAZASPIRO COMPOUNDS AND ITS USE | BIONOVA PHARMACEUTICALS (SHANGHAI) LIMITED (CN) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |
| CN-109743875-A | The inhibitor of MENIN-MLL interaction | 生命医药公司 | 2019-05-10 | — | — | CN | disclosed |
| WO-2012095707-A1 | PROCESS FOR THE PREPARATION OF NEBIVOLOL | MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A. (LU) | 2012-07-19 | — | — | WO | disclosed |
| EP-2457893-A1 | Intermediates for macrocyclic modulators of the ghrelin receptor | Tranzyme Pharma, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| US-20090198050-A1 | Macrocyclic Modulators of the Ghrelin Receptor | TRANZYME PHARMA INC. | 2009-08-06 | — | — | US | disclosed |
| WO-2008010022-A2 | A PROCESS FOR PREPARATION OF RACEMIC NEBIVOLOL | CIMEX PHARMA AG (US) | 2008-01-24 | — | — | WO | disclosed |
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | disclosed |
| EP-1803715-A1 | A process for preparation of racemic nebivolol | Cimex Pharma AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| WO-2004089911-A1 | PYRAZOLE DERIVATIVES AS GAMMA-SECRETASE INHIBITORS USEFUL IN THE TREATMENT OF ALZHEIMER’S DISEASE | MERCK SHARP & DOHME LIMITED (GB) | 2004-10-21 | — | — | WO | disclosed |