Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 12/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 12/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 12/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.46 |
| ▸ | F10 | P00742 | 10/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | HPN | P05981 | 3/20 | 0.43 |
| ▸ | HGFAC | Q04756 | 3/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316057 | 1.00 | PRSS1 (0.46) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL8313362 | 1.00 | PRSS1 (0.46) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL8948672 | 0.88 | F10 (0.57) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL8948668 | 0.88 | F10 (0.57) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL8948763 | 0.88 | F10 (0.57) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL8316694 | 0.88 | ITGB3 (0.56) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL8313193 | 0.86 | ITGB3 (0.51) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL8452739 | 0.85 | SIGMAR1 (0.44) | SIGMAR1GRM2 | |
| SCHEMBL8451456 | 0.85 | SIGMAR1 (0.44) | SIGMAR1GRM2 | |
| SCHEMBL8457744 | 0.85 | SIGMAR1 (0.44) | SIGMAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-B1 | Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 1999-06-30 | — | — | EP | disclosed |