Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452739 | 1.00 | SIGMAR1 (0.44) | SIGMAR1GRM2L3MBTL1HRH3MEN1 | |
| SCHEMBL8451456 | 1.00 | SIGMAR1 (0.44) | SIGMAR1GRM2L3MBTL1HRH3MEN1 | |
| SCHEMBL8450620 | 0.91 | GRM2 (0.42) | SIGMAR1GRM2L3MBTL1 | |
| SCHEMBL8948876 | 0.88 | SIGMAR1 (0.43) | SIGMAR1GRM2L3MBTL1HRH3 | |
| SCHEMBL8948720 | 0.88 | L3MBTL1 (0.49) | SIGMAR1GRM2L3MBTL1 | |
| SCHEMBL8948663 | 0.88 | L3MBTL1 (0.49) | SIGMAR1GRM2L3MBTL1 | |
| SCHEMBL8948589 | 0.88 | L3MBTL1 (0.49) | SIGMAR1GRM2L3MBTL1 | |
| SCHEMBL8452361 | 0.88 | GRM2 (0.51) | SIGMAR1GRM2 | |
| SCHEMBL8458486 | 0.88 | GRM2 (0.51) | SIGMAR1GRM2 | |
| SCHEMBL8948773 | 0.86 | SIGMAR1 (0.44) | SIGMAR1GRM2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-B1 | Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 1999-06-30 | — | — | EP | disclosed |
| EP-0623615-A1 | Adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |