Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311112 | 0.94 | CA2 (0.34) | CA2ARG1 | |
| SCHEMBL8310142 | 0.88 | ARG1 (0.32) | ARG1 | |
| SCHEMBL3048047 | 0.77 | CYP4F2 (0.37) | — | |
| SCHEMBL3035102 | 0.76 | CA1 (0.33) | CA2 | |
| SCHEMBL3035115 | 0.76 | GAA (0.36) | CA2 | |
| SCHEMBL8315940 | 0.75 | ARG1 (0.32) | CA2ARG1 | |
| SCHEMBL20437596 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL13322515 | 0.74 | CA1 (0.32) | CA2 | |
| SCHEMBL3043082 | 0.74 | CA2 (0.32) | CA2 | |
| SCHEMBL3037355 | 0.74 | MEN1 (0.30) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562439-B1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0562440-B1 | Imidazopyridazines as antiasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5491145-A | ANTIASTHMA, ANTI-PLATELET ACTIVATING FACTOR BRONCHOCONSTRICTION-INHIBITING AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| US-5482939-A | ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| US-5389633-A | ANTIASTHMATIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0562439-A1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0562440-A1 | Imidazopyridazines as antiasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |