Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313235 | 1.00 | F2 (0.49) | F2PRSS1CYP19A1EPHX1HPGD | |
| SCHEMBL3346269 | 0.85 | PDK1 (0.42) | F2PRSS1CYP19A1MMP2MMP9 | |
| SCHEMBL13424296 | 0.84 | CYP19A1 (0.41) | F2PRSS1CYP19A1MMP2MMP9 | |
| SCHEMBL3344769 | 0.82 | ACACB (0.41) | CYP19A1 | |
| SCHEMBL19590161 | 0.82 | MEN1 (0.45) | CYP19A1EPHX1MMP2MMP9ANPEP | |
| SCHEMBL1147395 | 0.82 | EPHX1 (0.44) | F2PRSS1CYP19A1EPHX1 | |
| SCHEMBL13424284 | 0.81 | MEP1B (0.38) | F2PRSS1CYP19A1 | |
| SCHEMBL28855000 | 0.81 | CYP1A2 (0.55) | LMNACYP1A2 | |
| SCHEMBL26276986 | 0.81 | CYP1A2 (0.55) | LMNACYP1A2 | |
| SCHEMBL607313 | 0.81 | CYP1A2 (0.55) | LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945448-A1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES, LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |