Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 18/20 | 0.47 |
| ▸ | MMP2 | P08253 | 18/20 | 0.47 |
| ▸ | MMP9 | P14780 | 13/20 | 0.47 |
| ▸ | MMP8 | P22894 | 12/20 | 0.47 |
| ▸ | MMP3 | P08254 | 7/20 | 0.47 |
| ▸ | MMP14 | P50281 | 6/20 | 0.47 |
| ▸ | MMP7 | P09237 | 4/20 | 0.47 |
| ▸ | MMP10 | P09238 | 3/20 | 0.47 |
| ▸ | MMP12 | P39900 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 6/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6205539 | 0.99 | MMP13 (0.47) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL6227284 | 0.92 | PHGDH (0.41) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL6206877 | 0.87 | MMP13 (0.37) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL8321550 | 0.84 | MMP13 (0.36) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL8316605 | 0.81 | MMP13 (0.46) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL8314092 | 0.81 | MMP2 (0.63) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL6697955 | 0.79 | MMP13 (0.60) | MMP13MMP2MMP9MMP8MMP3 | |
| Hydrochloric Acid SCHEMBL6206733 | 0.78 | MMP13 (0.59) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL8316685 | 0.77 | MMP2 (0.50) | MMP13MMP2MMP9MMP8MMP3 | |
| Hydrochloric Acid SCHEMBL6205781 | 0.76 | MMP2 (0.49) | MMP13MMP2MMP9MMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048368-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |