Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 16/20 | 0.63 |
| ▸ | MMP13 | P45452 | 16/20 | 0.63 |
| ▸ | MMP9 | P14780 | 12/20 | 0.63 |
| ▸ | MMP14 | P50281 | 9/20 | 0.63 |
| ▸ | MMP1 | P03956 | 9/20 | 0.57 |
| ▸ | MMP3 | P08254 | 8/20 | 0.57 |
| ▸ | MMP8 | P22894 | 8/20 | 0.57 |
| ▸ | MMP7 | P09237 | 5/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MMP10 | P09238 | 3/20 | 0.52 |
| ▸ | MMP12 | P39900 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697955 | 0.85 | MMP13 (0.60) | MMP2MMP13MMP9MMP14MMP1 | |
| Hydrochloric Acid SCHEMBL6206733 | 0.84 | MMP13 (0.59) | MMP2MMP13MMP9MMP14MMP1 | |
| SCHEMBL8316532 | 0.84 | MMP2 (0.57) | MMP2MMP13MMP9MMP14MMP1 | |
| SCHEMBL8316685 | 0.83 | MMP2 (0.50) | MMP2MMP13MMP9MMP14MMP1 | |
| Hydrochloric Acid SCHEMBL6205781 | 0.82 | MMP2 (0.49) | MMP2MMP13MMP9MMP14MMP1 | |
| SCHEMBL8317677 | 0.82 | MMP2 (0.55) | MMP2MMP13MMP9MMP14MMP1 | |
| SCHEMBL8316186 | 0.82 | MMP13 (0.58) | MMP2MMP13MMP9MMP14MMP1 | |
| SCHEMBL8316565 | 0.81 | MMP8 (0.60) | MMP2MMP13MMP9MMP14MMP1 | |
| Hydrochloric Acid SCHEMBL6208482 | 0.81 | MMP2 (0.48) | MMP2MMP13MMP9MMP14MMP1 | |
| SCHEMBL8313462 | 0.81 | MMP13 (0.47) | MMP2MMP13MMP9MMP14MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048368-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |