Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18289817 | 0.85 | RAB9A (0.58) | OPRD1RAB9ACA2CA12CA1 | |
| SCHEMBL28880171 | 0.85 | RAB9A (0.58) | OPRD1RAB9ACA2CA12CA1 | |
| SCHEMBL28912998 | 0.83 | RAB9A (0.47) | OPRD1RAB9ACA2CA12CA1 | |
| SCHEMBL18289932 | 0.78 | RAB9A (0.51) | OPRD1RAB9ACA2CHKASIGMAR1 | |
| SCHEMBL8795419 | 0.77 | SIGMAR1 (0.43) | OPRD1RAB9ACA2CA12CA1 | |
| SCHEMBL8310797 | 0.77 | CHRM5 (0.44) | RAB9ASIGMAR1CHRM5CHRM3 | |
| SCHEMBL8310688 | 0.76 | SIGMAR1 (0.41) | OPRD1CA2CA12CA1CA9 | |
| SCHEMBL6423835 | 0.76 | SIGMAR1 (0.42) | OPRD1RAB9ACA2CA12CA1 | |
| SCHEMBL27638795 | 0.74 | OPRD1 (0.39) | OPRD1CA2CA12CA1CA9 | |
| SCHEMBL905224 | 0.74 | SIGMAR1 (0.44) | OPRD1RAB9ACA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958373-A | Polychelants as contrast enhancing agents | NYCOMED SALUTAR INC. (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0717737-B1 | CHELANTS AS CONTRAST ENHANCING AGENTS | NYCOMED SALUTAR INC (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0717737-A1 | CHELANTS AS CONTRAST ENHANCING AGENTS | NYCOMED SALUTAR, INC. (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007270-A1 | CHELANTS AS CONTRAST ENHANCING AGENTS | NYCOMED SALUTAR, INC. (US) | 1995-03-16 | — | — | WO | disclosed |