Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314707 | 0.99 | ALDH1A1 (0.39) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL8562841 | 0.87 | HSD11B1 (0.40) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL8556727 | 0.78 | HSD11B1 (0.47) | ALDH1A1KDM4ESLC6A4DRD3SLC6A3 | |
| Hydrochloric Acid SCHEMBL1373203 | 0.76 | HSD11B1 (0.46) | ALDH1A1KDM4ESLC6A4DRD3SLC6A3 | |
| SCHEMBL8393125 | 0.76 | HSD11B1 (0.33) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL15374964 | 0.75 | PAOX (0.42) | ALDH1A1KDM4EDRD3TDP1SMN1; SMN2 | |
| SCHEMBL16923658 | 0.75 | PAOX (0.42) | ALDH1A1KDM4EDRD3TDP1SMN1; SMN2 | |
| SCHEMBL16920373 | 0.75 | HSD11B1 (0.38) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL16920375 | 0.75 | HSD11B1 (0.38) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL8478368 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EUSP2TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717737-B1 | CHELANTS AS CONTRAST ENHANCING AGENTS | NYCOMED SALUTAR INC (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0717737-A1 | CHELANTS AS CONTRAST ENHANCING AGENTS | NYCOMED SALUTAR, INC. (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007270-A1 | CHELANTS AS CONTRAST ENHANCING AGENTS | NYCOMED SALUTAR, INC. (US) | 1995-03-16 | — | — | WO | disclosed |