Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556727 | 0.89 | HSD11B1 (0.47) | HSD11B1HSD17B10ALDH1A1KDM4ETDP1 | |
| SCHEMBL8314707 | 0.89 | ALDH1A1 (0.39) | ALDH1A1KDM4ETDP1LMNAGAA | |
| Hydrochloric Acid SCHEMBL1373203 | 0.87 | HSD11B1 (0.46) | HSD11B1HSD17B10ALDH1A1KDM4ETDP1 | |
| SCHEMBL8313856 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KDM4ETDP1LMNAGAA | |
| SCHEMBL8393125 | 0.87 | HSD11B1 (0.33) | HSD11B1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL15374964 | 0.86 | PAOX (0.42) | HSD11B1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL16923658 | 0.86 | PAOX (0.42) | HSD11B1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL8669880 | 0.84 | HTR1A (0.43) | HSD17B10ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL5487629 | 0.83 | KDM4E (0.43) | HSD11B1ALDH1A1KDM4E | |
| SCHEMBL16758742 | 0.83 | HSD11B1 (0.47) | HSD11B1ALDH1A1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700392-B1 | USE OF MACROCYCLIC METAL COMPLEXES AS TEMPERATURE PROBES | SCHERING AG (DE) | 1998-12-09 | — | — | EP | disclosed |
| US-5747000-A | 1,4-7-TRIS-(CARBOXYMETHYL)-1,4,7,10-TETRAAZACYCLODODECANE DERIVATIVES; DETERMINING CHEMICAL SHIFT OF SIGNALS IN NUCLEAR MAGNETIC RESONANCE | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-05 | — | — | US | disclosed |
| EP-0700392-A1 | USE OF MACROCYCLIC METAL COMPLEXES AS TEMPERATURE PROBES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027977-A1 | USE OF MACROCYCLIC METAL COMPLEXES AS TEMPERATURE PROBES | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | disclosed |