Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348028 | 0.86 | PNMT (0.54) | PNMTOPRM1DRD4GRIN2DGRIN3B | |
| SCHEMBL8015804 | 0.86 | POLB (0.40) | OPRM1DRD4CYP2D6HSD11B1 | |
| Hydrochloric Acid SCHEMBL29535702 | 0.84 | PNMT (0.52) | PNMTOPRM1DRD4GRIN2DGRIN3B | |
| SCHEMBL25053841 | 0.78 | OPRM1 (0.36) | OPRM1DRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2677518 | 0.78 | CHRM2 (0.54) | OPRM1OPRD1CHRM2CHRM1OPRK1 | |
| SCHEMBL2677751 | 0.75 | HSD11B1 (0.42) | HSD11B1 | |
| SCHEMBL22918207 | 0.74 | HPGD (0.37) | KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2679166 | 0.73 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL2678582 | 0.73 | CHRM2 (0.49) | OPRM1OPRD1CHRM2CHRM1OPRK1 | |
| SCHEMBL4463296 | 0.71 | HSD11B1 (0.40) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915882-A1 | 1-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998007722-A1 | QUATERNARY AMMONIUM COMPOUNDS AS TACHYKININ ANTAGONIST | PFIZER LIMITED (GB) | 1998-02-26 | — | — | WO | disclosed |
| WO-1998004561-A1 | 1-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |