Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316989 | 0.86 | PTGDR2 (0.38) | NISCHSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL8312319 | 0.85 | NPC1 (0.37) | NISCHMAOBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8315862 | 0.80 | ALOX5 (0.44) | NISCHSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL8310827 | 0.80 | PIK3CD (0.40) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| SCHEMBL8316374 | 0.79 | MAPT (0.49) | NISCHMAOAMAOBSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8315893 | 0.79 | MAPT (0.38) | SMN1; SMN2ALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL8022992 | 0.79 | MGAM (0.46) | SMN1; SMN2NPC1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL8312117 | 0.78 | RAB9A (0.42) | NISCHSMN1; SMN2ALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL3575297 | 0.78 | MGAM (0.45) | MAOBSMN1; SMN2NPC1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL8316299 | 0.78 | LOXL2 (0.39) | IKBKBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351856-B1 | Thiazolo[5,4-b]azepine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-15 | — | — | EP | disclosed |