Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 18/20 | 0.71 |
| ▸ | MMP9 | P14780 | 15/20 | 0.71 |
| ▸ | MMP3 | P08254 | 14/20 | 0.71 |
| ▸ | MMP7 | P09237 | 13/20 | 0.71 |
| ▸ | MMP13 | P45452 | 16/20 | 0.64 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278385 | 1.00 | MMP1 (0.71) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL6808240 | 0.87 | MMP1 (0.59) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL7762105 | 0.85 | MMP1 (0.80) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL7341460 | 0.85 | MMP1 (0.80) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL7340402 | 0.84 | MMP1 (0.73) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL7375954 | 0.84 | MMP1 (0.79) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL6336332 | 0.84 | MMP1 (0.79) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL6338561 | 0.84 | MMP1 (0.79) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL6266281 | 0.81 | MMP1 (0.75) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL3943938 | 0.79 | MMP13 (0.90) | MMP1MMP9MMP3MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073599-A2 | INHIBITORS OF HEPATITIS C VIRUS, COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2004-09-02 | — | — | WO | disclosed |