Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21245483 | 0.92 | ALDH1A1 (0.64) | ALDH1A1TSHRDNM1TDP1CA12 | |
| Hydrochloric Acid SCHEMBL21245510 | 0.92 | ALDH1A1 (0.64) | ALDH1A1TSHRDNM1TDP1CA12 | |
| SCHEMBL1290871 | 0.91 | ALDH1A1 (0.75) | ALDH1A1TSHRDNM1TDP1CA12 | |
| SCHEMBL212626 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL17238883 | 0.87 | ALDH1A1 (0.69) | ALDH1A1TSHRDNM1TDP1CA12 | |
| SCHEMBL10790523 | 0.87 | ALDH1A1 (0.83) | ALDH1A1TSHRDNM1TDP1CA12 | |
| Bromide SCHEMBL30558707 | 0.87 | ALDH1A1 (0.69) | ALDH1A1TSHRDNM1TDP1CA12 | |
| SCHEMBL26135085 | 0.87 | ALDH1A1 (0.69) | ALDH1A1TSHRDNM1TDP1CA12 | |
| Iodide SCHEMBL21245472 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRDNM1TDP1CA12 | |
| Hydrochloric Acid SCHEMBL21245487 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRDNM1TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922640-A | COMPRISING A POROUS INORGANIC CARRIER, A COMPLEX OF NITROGEN CONTAINING COMPOUND AND A COPPER HALIDE, HIGH SELECTIVITY, EASILY DESORBED, RECOVERY BY TREATING WITH A REDUCING AGENT | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0792684-A2 | Novel adsorbent for carbon monoxide and method | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1997-09-03 | — | — | EP | disclosed |