Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336923 | 0.86 | ALOX15 (0.53) | ALOX15ALDH1A1SMN1; SMN2FFAR1MAPT | |
| SCHEMBL8828412 | 0.83 | ALOX15 (0.59) | ALOX15ALDH1A1SMN1; SMN2FFAR1MAPT | |
| SCHEMBL10886176 | 0.82 | GSK3B (0.57) | ALDH1A1GSK3BTRPA1MAPK1HIF1A | |
| SCHEMBL339492 | 0.82 | ALOX15 (0.81) | ALOX15ALDH1A1MAPK1SMN1; SMN2FFAR1 | |
| SCHEMBL11660630 | 0.81 | ALOX15 (0.57) | ALOX15ALDH1A1SMN1; SMN2FFAR1MAPT | |
| SCHEMBL11658609 | 0.81 | ALOX15 (0.57) | ALOX15ALDH1A1GSK3BSMN1; SMN2FFAR1 | |
| SCHEMBL458062 | 0.81 | GSK3B (0.59) | ALOX15ALDH1A1GSK3BSMN1; SMN2FFAR1 | |
| SCHEMBL7929301 | 0.81 | MEN1 (0.58) | ALOX15ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL1965751 | 0.81 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1MAPT | |
| SCHEMBL10886125 | 0.81 | L3MBTL1 (0.56) | ALDH1A1GSK3BTRPA1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |