Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4360696 | 0.86 | PLA2G4B (0.44) | ALOX15SMN1; SMN2MAPT | |
| SCHEMBL339492 | 0.85 | ALOX15 (0.81) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL29051537 | 0.83 | ALOX15 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL16035699 | 0.83 | ALOX15 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL341847 | 0.83 | ALOX15 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL5827387 | 0.83 | ALOX15 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL27341868 | 0.82 | MAPT (0.42) | ALOX15ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL10954272 | 0.81 | MAPT (0.59) | ALDH1A1MAPTTSHR | |
| SCHEMBL8314675 | 0.81 | ALOX15 (0.57) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL459533 | 0.80 | L3MBTL1 (0.66) | ALOX15ALDH1A1SMN1; SMN2FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509424-A1 | NOVEL OXADIAZOLE COMPOUNDS | Abbott Laboratories (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071570-A1 | NOVEL OXADIAZOLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | WO | disclosed |