Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.46 |
| ▸ | BRD2 | P25440 | 7/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 7/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318636 | 0.93 | BRD4 (0.47) | BRD4BRD2BRD3CYP11B1CYP11B2 | |
| SCHEMBL8321315 | 0.92 | BRD4 (0.39) | BRD4BRD2BRD3CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8319535 | 0.91 | BRD4 (0.38) | BRD4BRD2BRD3CYP11B1CYP11B2 | |
| SCHEMBL8321540 | 0.90 | BRD4 (0.43) | BRD4BRD2BRD3CYP11B1CYP11B2 | |
| SCHEMBL8317491 | 0.89 | HDAC3 (0.43) | BRD4BRD2BRD3 | |
| SCHEMBL8319774 | 0.86 | AR (0.41) | BRD4BRD2BRD3CYP11B1CYP11B2 | |
| SCHEMBL8320433 | 0.86 | BRS3 (0.39) | BRD4BRD2BRD3CYP11B1CYP11B2 | |
| SCHEMBL8316213 | 0.85 | BRD4 (0.55) | BRD4BRD2BRD3GABRA1GABRA5 | |
| SCHEMBL8318331 | 0.85 | BRD4 (0.49) | BRD4BRD2BRD3 | |
| SCHEMBL8319404 | 0.84 | BRD4 (0.47) | BRD4BRD2BRD3CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | claimed |
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |