Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | PNMT | P11086 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313494 | 0.89 | TDP2 (0.39) | TDP2AKR1B1MEN1KMT2AMAPT | |
| SCHEMBL8794691 | 0.81 | TDP2 (0.46) | TDP2AKR1B1MEN1KMT2AMAPT | |
| SCHEMBL8311388 | 0.73 | TDP2 (0.41) | TDP2MEN1KMT2AMAPTRAB9A | |
| SCHEMBL8539954 | 0.71 | NPC1 (0.44) | AKR1B1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL23705313 | 0.71 | MAPT (0.42) | TDP2AKR1B1MEN1KMT2AMAPT | |
| SCHEMBL10637355 | 0.70 | AKR1B1 (0.48) | TDP2AKR1B1MEN1KMT2AMAPT | |
| SCHEMBL9736807 | 0.69 | MALT1 (0.36) | AKR1B1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL983449 | 0.68 | MEN1 (0.51) | TDP2MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7766759 | 0.68 | MALT1 (0.51) | TDP2AKR1B1MEN1KMT2AMAPT | |
| SCHEMBL6987818 | 0.68 | TLR3 (0.46) | AKR1B1MEN1KMT2AMAPTTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |