Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PTPRC | P08575 | 3/20 | 0.30 |
| ▸ | S100A4 | P26447 | 2/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735707 | 0.85 | MALT1 (0.33) | MALT1MAPT | |
| SCHEMBL9736303 | 0.82 | MALT1 (0.36) | MALT1 | |
| SCHEMBL9736109 | 0.82 | CNR2 (0.35) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9737094 | 0.79 | MALT1 (0.35) | MALT1ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL9737016 | 0.79 | MALT1 (0.35) | MALT1ALDH1A1NR3C1PGRNR3C2 | |
| SCHEMBL9735717 | 0.79 | CCNE1 (0.34) | MALT1ALDH1A1NR3C1PGRNR3C2 | |
| SCHEMBL9736959 | 0.78 | KDM4E (0.33) | MALT1ALDH1A1NR3C1PGRNR3C2 | |
| SCHEMBL9734455 | 0.78 | MALT1 (0.35) | MALT1ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL9735261 | 0.74 | NR1H4 (0.38) | MALT1ALDH1A1NR3C1PGRNR3C2 | |
| SCHEMBL9737279 | 0.72 | CHRM2 (0.34) | MALT1ALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |