Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795683 | 0.83 | ALDH1A1 (0.40) | SMN1; SMN2KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8313582 | 0.78 | TLR3 (0.38) | SMN1; SMN2KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8316959 | 0.77 | ALDH1A1 (0.35) | SMN1; SMN2KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8313838 | 0.77 | ALDH1A1 (0.35) | SMN1; SMN2KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8794948 | 0.71 | ALDH1A1 (0.40) | SMN1; SMN2KMT2AALDH1A1MAPTMALT1 | |
| SCHEMBL8312851 | 0.70 | TLR3 (0.38) | SMN1; SMN2KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8796257 | 0.70 | ALDH1A1 (0.36) | SMN1; SMN2KMT2AALDH1A1MAPTMALT1 | |
| SCHEMBL15337524 | 0.68 | ALPL (0.44) | SMN1; SMN2KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL8317389 | 0.67 | TLR3 (0.38) | SMN1; SMN2KMT2AALDH1A1LMNAMGLL | |
| SCHEMBL8314386 | 0.67 | ALDH1A1 (0.38) | SMN1; SMN2KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |