Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | PHGDH | O43175 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313587 | 0.88 | L3MBTL1 (0.41) | TLR3TLR9TLR8MALT1NR3C1 | |
| SCHEMBL8313582 | 0.85 | TLR3 (0.38) | TLR3TLR9TLR8MGLLMALT1 | |
| SCHEMBL8796400 | 0.83 | ALDH1A1 (0.38) | MALT1NR3C1PGRNR3C2AR | |
| SCHEMBL8312851 | 0.82 | TLR3 (0.38) | TLR3TLR9TLR8MALT1OPRD1 | |
| SCHEMBL8314196 | 0.79 | TLR3 (0.34) | TLR3TLR9TLR8MALT1NR3C1 | |
| SCHEMBL8316194 | 0.77 | ALDH1A1 (0.33) | MGLLNR3C1PGRNR3C2AR | |
| SCHEMBL8316094 | 0.76 | TLR3 (0.35) | TLR3TLR9TLR8MALT1KMT2A | |
| SCHEMBL8796257 | 0.75 | ALDH1A1 (0.36) | MALT1NR3C1PGRNR3C2AR | |
| SCHEMBL8317269 | 0.71 | AKR1B1 (0.38) | MALT1KMT2AALDH1A1SMN1; SMN2AKR1B1 | |
| SCHEMBL9566816 | 0.71 | ALDH1A1 (0.41) | TLR3MGLLNR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |