Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027345 | 0.94 | RAB9A (0.54) | SMN1; SMN2KMT2ATDP1HTTL3MBTL1 | |
| SCHEMBL28731533 | 0.88 | ALDH1A1 (0.50) | SMN1; SMN2KMT2ATDP1HTTL3MBTL1 | |
| SCHEMBL28731537 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2KMT2ATDP1HTTL3MBTL1 | |
| SCHEMBL16756229 | 0.82 | KMT2A (0.64) | SMN1; SMN2KMT2ATDP1HTTL3MBTL1 | |
| SCHEMBL8315096 | 0.81 | MAPT (0.51) | SMN1; SMN2KMT2ATDP1HTTL3MBTL1 | |
| SCHEMBL7978485 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2ATDP1HTTL3MBTL1 | |
| SCHEMBL3499943 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2ATDP1HTTL3MBTL1 | |
| SCHEMBL16756223 | 0.78 | ESR1 (0.63) | SMN1; SMN2KMT2ATDP1HTTL3MBTL1 | |
| SCHEMBL8320004 | 0.78 | POLB (0.63) | SMN1; SMN2KMT2ATDP1HTTL3MBTL1 | |
| SCHEMBL28448328 | 0.77 | ALDH1A1 (0.52) | KMT2ATDP1HTTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330432-A2 | SUBSTITUTED ALKANOIC ACIDS | Aventis Pharma Limited (GB) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002036553-A2 | SUBSTITUTED ALKANOIC ACIDS | AVENTIS PHARMA LIMITED (GB) | 2002-05-10 | — | — | WO | disclosed |