SCHEMBL831513

SCHEMBL831513

CCc1cc(C(=O)c2cc(CC)c(N)c(CC)c2)cc(CC)c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.47
POLB P06746 1/20 0.47
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
USP2 O75604 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PTGS2 P35354 4/20 0.37
PTGS1 P23219 3/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
GABRA2 P47869 1/20 0.37
GABRB2 P47870 1/20 0.37
GABRA4 P48169 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL942114 0.86 HDAC1 (0.44) HTTPOLBRAB9ASMN1; SMN2NPC1
SCHEMBL3943078 0.85 PPARG (0.43) HTTPOLBRAB9ASMN1; SMN2NPC1
SCHEMBL3946146 0.81 GABRP (0.45) RAB9ASMN1; SMN2NPC1USP2HSD17B10
SCHEMBL6901103 0.79 CA12 (0.50) HTTPOLBUSP2HSD17B10ALDH1A1
SCHEMBL8092896 0.78 GABRA1 (0.48) PTGS1GABRA1GABRB1GABRB2HSP90AA1
SCHEMBL7929919 0.77 CA1 (0.58) SMN1; SMN2NPC1HSD17B10ALDH1A1MAPT
SCHEMBL7898540 0.76 NPC1 (0.53) HTTPOLBRAB9ASMN1; SMN2NPC1
SCHEMBL3939114 0.76 ALDH1A1 (0.44) HTTPOLBRAB9ASMN1; SMN2NPC1
SCHEMBL10382471 0.75 POLB (0.50) HTTPOLBPTGS1GABRPGABRD
SCHEMBL27628872 0.74 ALDH1A1 (0.46) HTTPOLBRAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130165603-A1 Adhesive Composition And Adhesive Film Comprising The Same CHEIL INDUSTRIES, INC. (KR) 2013-06-27 US claimed
US-5059672-A Polyurea coatings; high tensile strength, chemical and corrosion resistant THARE COAT, INC. (US) 1991-10-22 US claimed
US-20230017689-A1 PREPREG, LAMINATE, AND INTEGRATED PRODUCT TORAY INDUSTRIES, INC. (JP) 2023-01-19 US disclosed
EP-3623870-B1 IMAGE FORMING APPARATUS AND TONER SET RICOH CO LTD (JP) 2022-05-04 EP disclosed
US-11281117-B2 Toner for electrostatic-image development and method for manufacturing same ZEON CORPORATION (JP) 2022-03-22 US disclosed
EP-3418811-B1 TONER, DEVELOPER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND METHOD FOR MANUFACTURING TONER RICOH CO LTD (JP) 2021-07-28 EP disclosed
WO-2021117465-A1 PREPREG, LAMINATE AND INTEGRATED MOLDED ARTICLE 東レ株式会社 2021-06-17 WO disclosed
EP-3144728-B1 TONER BINDER, AND TONER SANYO CHEMICAL IND LTD (JP) 2021-04-21 EP disclosed
US-10895816-B2 Image forming apparatus and toner set RICOH COMPANY, LTD. (JP) 2021-01-19 US disclosed
US-20210002441-A1 RESIN PARTICLES AND METHOD FOR PRODUCING SAME SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-07 US disclosed
US-20200089140-A1 IMAGE FORMING APPARATUS AND TONER SET RICOH COMPANY, LTD. (JP) 2020-03-19 US disclosed
US-4820743-A BLEND OF POLYETHERPOLYOL AND POLYAMINE, AND UNSATURATED MONOMER SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-11 US disclosed
EP-0245864-A2 Cyclohexanedimethanol/diamine mixtures as RIM extenders THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
EP-0219709-A2 Polymethylene polyphenylamine modified diamine chain extenders and polyurea elastomers therefrom THE DOW CHEMICAL COMPANY (US) 1987-04-29 EP disclosed
US-4659747-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1987-04-21 US disclosed
EP-0185369-A2 Polyamide-polyurea polymers THE DOW CHEMICAL COMPANY (US) 1986-06-25 EP disclosed
US-4552945-A REACTION INJECTION MOLDING, POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1985-11-12 US disclosed
EP-0075130-A2 Improved reaction injection molding process THE DOW CHEMICAL COMPANY (US) 1983-03-30 EP disclosed
US-4374210-A MOLDING MATERIALS; LONG GELATION TIME; STOICHIOMETRY; INJECTION MOLDING THE UPJOHN COMPANY (US) 1983-02-15 US disclosed
US-4296212-A MOLDING MATERIALS THE UPJOHN COMPANY (US) 1981-10-20 US disclosed