Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315816 | 0.95 | MEN1 (0.32) | GAAEPHX1HPGDBTKCHRM2 | |
| SCHEMBL3694198 | 0.81 | GABRP (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL9998422 | 0.81 | EPHX1 (0.36) | EPHX1FDPSCHRM2CHRM1CHRM3 | |
| SCHEMBL9685631 | 0.79 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL11166441 | 0.79 | GLI1 (0.38) | — | |
| Ammonia Solution, Strong SCHEMBL16191692 | 0.79 | EPHX1 (0.35) | EPHX1FDPSCHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8933166 | 0.78 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL29291158 | 0.77 | — | — | |
| SCHEMBL7590352 | 0.77 | — | — | |
| SCHEMBL27508951 | 0.76 | MEN1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-B1 | Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 1999-06-30 | — | — | EP | disclosed |
| EP-0623615-A1 | Adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |