Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315133 | 0.95 | GAA (0.33) | HPGDBTKCHRM2CHRM1CHRM3 | |
| SCHEMBL11166441 | 0.84 | GLI1 (0.38) | — | |
| SCHEMBL3694198 | 0.82 | GABRP (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL27508951 | 0.82 | MEN1 (0.40) | MEN1BLMKMT2A | |
| SCHEMBL7590352 | 0.79 | — | — | |
| SCHEMBL29291158 | 0.79 | — | — | |
| SCHEMBL6223489 | 0.79 | SLC6A3 (0.36) | MEN1BLMKMT2A | |
| SCHEMBL2330804 | 0.79 | SLC6A3 (0.36) | MEN1BLMKMT2A | |
| SCHEMBL27478695 | 0.77 | MEN1 (0.34) | MEN1BLMKMT2A | |
| Hydrochloric Acid SCHEMBL902096 | 0.77 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-B1 | Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 1999-06-30 | — | — | EP | disclosed |
| EP-0623615-A1 | Adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |