Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713564 | 0.93 | MAPK1 (0.55) | MAPK1ALDH1A1SMN1; SMN2RXFP1TSHR | |
| SCHEMBL4713091 | 0.77 | ALDH1A1 (0.54) | MAPK1ALDH1A1SMN1; SMN2RXFP1TSHR | |
| SCHEMBL4714178 | 0.77 | LMNA (0.57) | MAPK1ALDH1A1SMN1; SMN2RXFP1TSHR | |
| SCHEMBL4717827 | 0.76 | MAPK1 (0.61) | MAPK1ALDH1A1SMN1; SMN2RXFP1TSHR | |
| SCHEMBL5739571 | 0.76 | SMN1; SMN2 (0.52) | MAPK1ALDH1A1SMN1; SMN2RXFP1TSHR | |
| SCHEMBL4715769 | 0.76 | RXFP1 (0.58) | MAPK1ALDH1A1SMN1; SMN2RXFP1KDM4E | |
| SCHEMBL4714610 | 0.76 | MAPK1 (0.55) | MAPK1ALDH1A1SMN1; SMN2RXFP1TSHR | |
| SCHEMBL4713063 | 0.75 | MAPT (0.54) | MAPK1ALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL4716402 | 0.74 | ALDH1A1 (0.58) | MAPK1ALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL4713650 | 0.73 | MAPK1 (0.65) | MAPK1ALDH1A1SMN1; SMN2RXFP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092135-A2 | SUBSTITUTED BENZOSULPHONAMIDE AS POTENTIATORS OF GLUTAMATE RECEPTORS | ASTRAZENECA (SE) | 2004-10-28 | — | — | WO | disclosed |