Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8316038 | 0.75 | SMN1; SMN2 (0.48) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL8316036 | 0.75 | SMN1; SMN2 (0.48) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL8311908 | 0.74 | KDM1A (0.37) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL4882825 | 0.66 | NPC1 (0.49) | BRD4NPC1ALDH1A1LMNAPOLB | |
| SCHEMBL4812511 | 0.62 | NR4A2 (0.43) | BRD4 | |
| SCHEMBL8312511 | 0.60 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8316741 | 0.59 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL5666175 | 0.59 | P2RX7 (0.46) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8316739 | 0.59 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL6265796 | 0.59 | TLR8 (0.51) | BRD4NPC1ALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443588-B1 | Condensed thiazole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-23 | — | — | EP | claimed |