Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315255 | 0.74 | HDAC1 (0.38) | NPC1ALDH1A1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL8313796 | 0.73 | HDAC1 (0.44) | KDM1AKDM4ENPC1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL8316036 | 0.73 | SMN1; SMN2 (0.48) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8316038 | 0.73 | SMN1; SMN2 (0.48) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8315616 | 0.69 | MAPT (0.52) | KDM1ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8316629 | 0.66 | RAB9A (0.50) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8313443 | 0.65 | ALDH1A1 (0.54) | NPC1ALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8316926 | 0.65 | NFE2L2 (0.52) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23573535 | 0.64 | KDM1A (0.41) | KDM1ASCN9ABTKIDO1 | |
| SCHEMBL8311160 | 0.64 | RAB9A (0.53) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443588-B1 | Condensed thiazole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-23 | — | — | EP | claimed |
| EP-0443588-A1 | Condensed thiazole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-28 | — | — | EP | claimed |
| EP-0443588-B1 | Condensed thiazole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5153201-A | Inhibitors of lipoperoxide and lipoxygenase; antiischemic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0443588-A1 | Condensed thiazole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-28 | — | — | EP | disclosed |