Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 8/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310770 | 0.82 | APP (0.47) | APPKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8311214 | 0.75 | S1PR1 (0.39) | KDM4ES1PR1 | |
| SCHEMBL8311144 | 0.75 | ESR1 (0.48) | ESR1ESR2APPPDE4DKDM4E | |
| SCHEMBL8311728 | 0.73 | S1PR1 (0.38) | LMNAS1PR1 | |
| SCHEMBL27294716 | 0.70 | ESR1 (0.49) | ESR1ESR2APPPDE4DKDM4E | |
| SCHEMBL8310912 | 0.70 | MIF (0.54) | ESR1ESR2APPKDM4EALDH1A1 | |
| SCHEMBL9750010 | 0.68 | GAA (0.53) | ESR1ESR2APPKDM4EALDH1A1 | |
| SCHEMBL6600736 | 0.67 | ESR1 (0.48) | ESR1ESR2APPPDE4DKDM4E | |
| SCHEMBL8311101 | 0.66 | KDM4E (0.48) | ESR1ESR2APPPDE4DKDM4E | |
| SCHEMBL29941531 | 0.65 | ESR1 (1.00) | ESR1ESR2APPPDE4DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| CN-1036589-C | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-12-03 | — | — | CN | disclosed |
| CN-1033088-C | Thiazolylbenzofuran derivatives, processes for preparation thereof and pharmaceutical composition comprising same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-23 | — | — | CN | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| CN-1074444-A | New thiazolyl benzofuran derivative, its preparation method and contain the pharmaceutical composition of this derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-07-21 | — | — | CN | disclosed |
| CN-1070910-A | New thiazolyl benzofuran derivative, its preparation method and contain the pharmaceutical composition of this derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-04-14 | — | — | CN | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |