Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530176 | 0.88 | KCNA3 (0.50) | KCNA3PRSS1LTA4HL3MBTL1TMPRSS2 | |
| SCHEMBL11613225 | 0.83 | KCNA3 (0.52) | KCNA3PRSS1L3MBTL1TMPRSS2PRMT1 | |
| SCHEMBL221617 | 0.81 | CYP3A4 (0.50) | KCNA3 | |
| SCHEMBL11615899 | 0.80 | KCNA3 (0.55) | KCNA3PRSS1L3MBTL1TMPRSS2PRMT1 | |
| SCHEMBL2015358 | 0.79 | DRD4 (0.52) | LTA4HL3MBTL1DRD2DRD4DRD3 | |
| SCHEMBL2096254 | 0.79 | LTA4H (0.57) | LTA4HGAA | |
| SCHEMBL15977888 | 0.78 | KCNA3 (0.38) | KCNA3PRSS1LTA4HL3MBTL1TMPRSS2 | |
| SCHEMBL14095592 | 0.78 | PRMT1 (0.54) | KCNA3PRSS1L3MBTL1TMPRSS2PRMT1 | |
| SCHEMBL4218226 | 0.77 | DRD2 (0.52) | L3MBTL1DRD2DRD4DRD3 | |
| SCHEMBL4692348 | 0.77 | LTA4H (0.59) | LTA4HDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958294-A1 | 2-(1,2,4-TRIAZOLE-1-YL)-1,3,4-THIADIAZOLE DERIVATIVES HAVING AN EFFECT ON THE C.N.S. AND THE HEART | EGIS GYOGYSZERGYAR (HU) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998030561-A1 | 2-(1,2,4-TRIAZOLE-1-YL)-1,3,4-THIADIAZOLE DERIVATIVES HAVING AN EFFECT ON THE C.N.S. AND THE HEART | EGIS Gyógyszergyár Rt. (HU) | 1998-07-16 | — | — | WO | disclosed |