⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21808019 | 0.73 | — | — | |
| SCHEMBL979388 | 0.68 | — | — | |
| SCHEMBL28010060 | 0.65 | — | — | |
| SCHEMBL27543267 | 0.65 | DYRK1A (0.39) | — | |
| SCHEMBL30568075 | 0.65 | DYRK1A (0.42) | — | |
| SCHEMBL2780319 | 0.65 | DYRK1A (0.42) | — | |
| SCHEMBL31039568 | 0.64 | TRPA1 (0.33) | — | |
| SCHEMBL12391372 | 0.64 | TRPA1 (0.33) | — | |
| SCHEMBL28232147 | 0.64 | CYP2A6 (0.33) | — | |
| SCHEMBL21808028 | 0.62 | IMPDH2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628046-B1 | TRIAZOLOPYRIMIDIN DERIVATIVES AS ANTIOTENSIN II RECEPTOR ANTAGONISTS | UNION PHARMA SCIENT APPL (FR) | 1999-05-12 | — | — | EP | disclosed |
| EP-0628046-A1 | TRIAZOLOPYRIMIDIN DERIVATIVES AS ANTIOTENSIN II RECEPTOR ANTAGONISTS | LABORATOIRES UPSA (FR) | 1994-12-14 | — | — | EP | disclosed |
| EP-0628045-A1 | PYRAZOLOPYRIMIDIN DERIVATIVES AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | LABORATOIRES UPSA (FR) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993017023-A1 | PYRAZOLOPYRIMIDIN DERIVATIVES AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | LABORATOIRES UPSA (FR) | 1993-09-02 | — | — | WO | disclosed |
| WO-1993017024-A1 | TRIAZOLOPYRIMIDIN DERIVATIVES AS ANTIOTENSIN II RECEPTOR ANTAGONISTS | LABORATOIRES UPSA (FR) | 1993-09-02 | — | — | WO | disclosed |