SCHEMBL8315689

SCHEMBL8315689

N#CC1=CC(CF)(CF)Oc2ccc(Br)cc21

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8317753 0.83 MAPKAPK2 (0.32)
SCHEMBL8318784 0.73 NPSR1 (0.32)
SCHEMBL8313504 0.71
SCHEMBL5269692 0.71 NR3C1 (0.37)
SCHEMBL8317275 0.69 NPSR1 (0.34)
SCHEMBL1977431 0.62 MAPT (0.43)
SCHEMBL2683150 0.60 NPSR1 (0.31)
SCHEMBL23362956 0.59 CA1 (0.43) AHR
SCHEMBL29804089 0.59 CA1 (0.43) AHR
SCHEMBL14862508 0.57 PGR (0.39) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0632033-B1 NOVEL BENZOPYRAN DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 1999-04-07 EP disclosed
US-5646308-A POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1997-07-08 US disclosed
EP-0632033-A1 NOVEL BENZOPYRAN DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1995-01-04 EP disclosed