Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 6/20 | 0.43 |
| ▸ | PRKCA | P17252 | 6/20 | 0.43 |
| ▸ | PRKCH | P24723 | 6/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 6/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317497 | 0.90 | CYP3A4 (0.45) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL8317078 | 0.87 | CAMK2D (0.48) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| Hydrochloric Acid SCHEMBL8318720 | 0.86 | CAMK2D (0.48) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL8316483 | 0.81 | CAMK2D (0.51) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| Hydrochloric Acid SCHEMBL8316493 | 0.80 | CAMK2D (0.42) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL8317092 | 0.79 | ROCK2 (0.45) | PRKCBPRKCACAMK2DMAPTHSD17B10 | |
| SCHEMBL8319658 | 0.79 | ROCK2 (0.45) | PRKCBPRKCACAMK2DMAPTHSD17B10 | |
| SCHEMBL8314832 | 0.79 | CAMK2D (0.43) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| Hydrochloric Acid SCHEMBL8319262 | 0.78 | ROCK2 (0.44) | PRKCBPRKCACAMK2DMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL8317707 | 0.78 | CAMK2D (0.42) | PRKCBPRKCAPRKCHPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925296-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011102-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1998-03-19 | — | — | WO | disclosed |