Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | CASP1 | P29466 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987418 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL28987404 | 0.81 | KMT2A (0.54) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL8315780 | 0.80 | TAS1R3 (0.55) | ALDH1A1KDM4EHPGDAPPCA12 | |
| SCHEMBL31474881 | 0.79 | LCK (0.72) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL28987439 | 0.79 | LCK (0.72) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL28987412 | 0.78 | PPP5C (0.60) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL31474878 | 0.75 | KMT2A (0.66) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL10812793 | 0.75 | KMT2A (0.66) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL31044605 | 0.74 | TAS1R3 (0.55) | ALDH1A1KDM4EHPGDAPPCA12 | |
| SCHEMBL31474875 | 0.71 | PPP5C (0.59) | ALDH1A1KMT2AKDM4EMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974828-B | Compounds as protein phosphatase 5 agonists, methods of preparation and uses thereof | 中国药科大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-115974828-A | Compound as protein phosphatase 5 agonist and preparation method and application thereof | 中国药科大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-108078976-B | Application of the IMCA in preparation anti-gastric cancer medicament | 河南大学 | 2019-12-03 | — | — | CN | disclosed |
| CN-108175766-B | Application of the IMCA in preparation anti-colorectal cancer medicament | 河南大学 | 2019-12-03 | — | — | CN | disclosed |
| CN-108014103-B | IMCA is preparing the application in antithyroid cancer drug | 河南大学 | 2019-12-03 | — | — | CN | disclosed |