Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TLR3 | O15455 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27330130 | 0.84 | CA9 (0.50) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL3193294 | 0.81 | TLR3 (0.59) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL14567130 | 0.78 | MEN1 (0.39) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL8316093 | 0.78 | PTGS1 (0.47) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL6976994 | 0.76 | PTGS1 (0.62) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL6270431 | 0.75 | MEN1 (0.46) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL8134327 | 0.74 | KMT2A (0.43) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL6267705 | 0.74 | CA9 (0.42) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL9205782 | 0.73 | CA9 (0.44) | CA9CA12CA1MEN1KMT2A | |
| SCHEMBL928563 | 0.73 | CA9 (0.44) | CA9CA12CA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| CN-1036918-C | Novel benzopyran derivatives | CHUGAI SEIYAKU PHARMACEUTICAL (JP) | 1998-01-07 | — | — | CN | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |
| CN-1077954-A | New 1-benzopyran derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1993-11-03 | — | — | CN | disclosed |