Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.57 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065909 | 0.87 | TLR3 (0.59) | TLR3HIF1AEPAS1CA9CA12 | |
| SCHEMBL2861820 | 0.87 | TLR3 (0.59) | TLR3HIF1AEPAS1CA9CA12 | |
| SCHEMBL6976994 | 0.82 | PTGS1 (0.62) | TLR3HIF1AEPAS1CA9CA12 | |
| SCHEMBL8315997 | 0.81 | CA9 (0.49) | TLR3HIF1AEPAS1CA9CA12 | |
| SCHEMBL8316093 | 0.81 | PTGS1 (0.47) | TLR3HIF1AEPAS1CA9CA12 | |
| SCHEMBL12155549 | 0.79 | ALDH1A1 (0.51) | TLR3HIF1AEPAS1CA1MEN1 | |
| SCHEMBL27330130 | 0.79 | CA9 (0.50) | TLR3HIF1AEPAS1CA9CA12 | |
| SCHEMBL928563 | 0.79 | CA9 (0.44) | TLR3HIF1AEPAS1CA9CA12 | |
| SCHEMBL9205782 | 0.79 | CA9 (0.44) | TLR3HIF1AEPAS1CA9CA12 | |
| SCHEMBL3258594 | 0.79 | CA9 (0.44) | TLR3HIF1AEPAS1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1535918-B1 | PROCESS FOR PRODUCING AMINOBENZOPYRAN COMPOUND | NISSAN CHEMICAL IND LTD (JP) | 2010-11-03 | — | — | EP | claimed |
| US-7683189-B2 | Process for producing aminobenzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-03-23 | — | — | US | claimed |
| US-20050192444-A1 | Process for producing aminobenzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-01 | — | — | US | claimed |
| EP-1535918-A1 | PROCESS FOR PRODUCING AMINOBENZOPYRAN COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2005-06-01 | — | — | EP | claimed |
| US-9745280-B2 | Compound or pharmaceutically acceptable salt thereof, and pharmaceutical composition containing same as active ingredient | SNU R&DB FOUNDATION (KR) | 2017-08-29 | — | — | US | disclosed |
| US-20160168161-A1 | METHOD FOR PRODUCING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL INDUSTIES, LTD. (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168161-A1 | METHOD FOR PRODUCING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL INDUSTIES, LTD. (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168161-A1 | METHOD FOR PRODUCING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL INDUSTIES, LTD. (JP) | 2016-06-16 | — | — | US | disclosed |
| EP-3026047-A1 | METHOD FOR PRODUCING HETEROCYCLIC COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2016-06-01 | — | — | EP | disclosed |
| CN-105377826-A | Process for producing heterocyclic compound | NISSAN CHEMICAL IND LTD | 2016-03-02 | — | — | CN | disclosed |
| CN-102190661-B | Tricyclic benzopyran compound as anti-arrhythmic agents | NISSAN CHEMICAL IND LTD | 2013-07-31 | — | — | CN | disclosed |
| US-8394974-B2 | Process for producing optically active chromene oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-12 | — | — | US | disclosed |
| EP-1109801-A1 | SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2001-06-27 | — | — | EP | disclosed |
| CN-1270169-A | Benzopyrane derivatives and preparation thereof | SMITHKLINE BEECHAM PLC (GB) | 2000-10-18 | — | — | CN | disclosed |
| WO-2000014084-A1 | SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2000-03-16 | — | — | WO | disclosed |
| CN-1036918-C | Novel benzopyran derivatives | CHUGAI SEIYAKU PHARMACEUTICAL (JP) | 1998-01-07 | — | — | CN | disclosed |
| US-5164509-A | BENZODIAZOLO ANALOGS | E. R. SQUIBB & SONS, INC. (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0488107-A2 | Tricyclic benzodiazole analogs and their use in the treatment of cardiovascular disorders | E.R. SQUIBB & SONS, INC. (US) | 1992-06-03 | — | — | EP | disclosed |
| CN-1047672-A | PYRANYL CYANOGUANIDINE DERIVATIVES | SQUIBB & SONS INC (US) | 1990-12-12 | — | — | CN | disclosed |
| US-4110347-A | ANTIHYPERTENSIVE | BEECHAM GROUP LIMITED (GB) | 1978-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192444-A1 | Process for producing aminobenzopyran compound | ALDH7A1, ACMSD, MANBA | TLR3 4641/4885HIF1A 404/4885EPAS1 3320/4885 |
| US-20160168161-A1 | METHOD FOR PRODUCING HETEROCYCLIC COMPOUND | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NAT1, NAT10 | TLR3 4339/4885HIF1A 3098/4885EPAS1 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.