Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662638 | 0.85 | OPRM1 (0.44) | OPRM1OPRD1ABCB11KCNH2OPRK1 | |
| SCHEMBL3662643 | 0.85 | OPRM1 (0.44) | OPRM1OPRD1ABCB11KCNH2OPRK1 | |
| SCHEMBL13462407 | 0.82 | OPRM1 (0.57) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5388533 | 0.82 | OPRD1 (0.79) | OPRM1OPRD1ABCB11KCNH2OPRK1 | |
| SCHEMBL8316576 | 0.79 | OPRD1 (0.60) | OPRM1OPRD1ABCB11KCNH2OPRK1 | |
| SCHEMBL14415620 | 0.79 | OPRD1 (0.65) | OPRM1OPRD1ABCB11KCNH2OPRK1 | |
| SCHEMBL8315518 | 0.79 | OPRM1 (0.46) | OPRM1OPRD1ABCB11KCNH2OPRK1 | |
| SCHEMBL8314826 | 0.77 | OPRD1 (0.50) | OPRM1OPRD1ABCB11KCNH2OPRK1 | |
| SCHEMBL2457390 | 0.77 | OPRD1 (0.61) | OPRM1OPRD1ABCB11KCNH2OPRK1 | |
| Hydrochloric Acid SCHEMBL7647391 | 0.75 | OPRD1 (0.59) | OPRM1OPRD1ABCB11KCNH2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |