SCHEMBL8316158

SCHEMBL8316158

CCCCCCC(SCC)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.59
FFAR1 O14842 2/20 0.59
MAPT P10636 1/20 0.52
LCK P06239 1/20 0.52
PPARD Q03181 1/20 0.52
ZDHHC20 Q5W0Z9 1/20 0.52
ZDHHC2 Q9UIJ5 1/20 0.52
ACE2 Q9BYF1 1/20 0.48
HSD17B10 Q99714 1/20 0.45
GRIK1 P39086 2/20 0.44
GRIK2 Q13002 2/20 0.44
FFAR4 Q5NUL3 1/20 0.44
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
CA2 P00918 1/20 0.41
HSPD1 P10809 1/20 0.41
BLM P54132 1/20 0.41
HSPE1 P61604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17255855 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL7750264 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8744934 0.92 HSD17B10 (0.51) GPR84FFAR1MAPTLCKPPARD
SCHEMBL17244841 0.88 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL9108501 0.86 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8856265 0.86 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8208596 0.86 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8856129 0.86 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8856116 0.86 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL11344216 0.86 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3962917-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS Momentive Performance Materials Inc. (US) 2022-03-09 EP claimed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN claimed
EP-3884018-A1 JASMOL Symrise AG (DE) 2021-09-29 EP claimed
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-02-16 US claimed
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. 2020-11-05 US claimed
WO-2020223068-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-11-05 WO claimed
EP-3962917-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS Momentive Performance Materials Inc. (US) 2022-03-09 EP disclosed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN disclosed
EP-3884018-A1 JASMOL Symrise AG (DE) 2021-09-29 EP disclosed
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-02-16 US disclosed
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. 2020-11-05 US disclosed
WO-2020223068-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-11-05 WO disclosed
WO-2017046058-A1 PERFUME COMPOSITION HAVING ODOR MODULATOR COMPOUNDS FOR INCREASING ODOR INTENSITY HENKEL AG & CO. KGAA (DE) 2017-03-23 WO disclosed
EP-0871620-A4 BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS ENZYMED INC (US) 1999-10-27 EP disclosed
EP-0871620-A1 BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS ENZYMED, Inc. (US) 1998-10-21 EP disclosed
WO-1997010233-A9 BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS 1997-05-09 WO disclosed
WO-1997010233-A1 BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS ENZYMED, INC. (US) 1997-03-20 WO disclosed
WO-1996005511-A1 BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS ENZYMED, INC. (US) 1996-02-22 WO disclosed
EP-0576287-A1 Cosmetic compositions UNILEVER PLC (GB) 1993-12-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters TST, MPST, APEH GPR84 4409/4885FFAR1 2684/4885MAPT 3621/4885
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS TST, MPST, APEH GPR84 4409/4885FFAR1 2684/4885MAPT 3621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.