Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913063 | 0.90 | CA12 (0.40) | CA12CA1CA2CA9CHRM1 | |
| SCHEMBL6913059 | 0.90 | CA12 (0.40) | CA12CA1CA2CA9CHRM1 | |
| SCHEMBL8317848 | 0.72 | CHRM1 (0.56) | CHRM1 | |
| SCHEMBL8317844 | 0.72 | CHRM1 (0.56) | CHRM1 | |
| SCHEMBL8505039 | 0.66 | CHRM1 (0.58) | CHRM1 | |
| SCHEMBL8505043 | 0.66 | CHRM1 (0.58) | CHRM1 | |
| SCHEMBL10426699 | 0.64 | NFE2L2 (0.42) | GPR119 | |
| SCHEMBL10426697 | 0.64 | NFE2L2 (0.42) | GPR119 | |
| SCHEMBL8320010 | 0.63 | CA12 (0.54) | CA12CA1CA2CA9ABCB1 | |
| SCHEMBL13407356 | 0.62 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874828-A4 | COMPOSITION FOR TREATING PAIN | LILLY CO ELI (US) | 1999-09-01 | — | — | EP | disclosed |
| EP-0874828-A1 | COMPOSITION FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997020819-A1 | COMPOSITION FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1997-06-12 | — | — | WO | disclosed |