Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201667 | 0.81 | DPP4 (0.50) | CTSKCTSLCTSBCTSS | |
| SCHEMBL5203358 | 0.80 | CTSK (0.50) | CTSKCTSLCTSBCTSSELANE | |
| SCHEMBL14899491 | 0.77 | CTSK (0.52) | CTSKCTSLCTSBCTSSHDAC8 | |
| SCHEMBL3611500 | 0.77 | CTSK (0.50) | CTSKCTSLCTSBCTSSELANE | |
| SCHEMBL22169449 | 0.77 | CTSK (0.50) | CTSKCTSLCTSBCTSSELANE | |
| SCHEMBL14899603 | 0.76 | DPP4 (0.55) | CTSKCTSLCTSBCTSSHDAC8 | |
| SCHEMBL5201959 | 0.73 | DPP4 (0.59) | CTSKCTSLCTSBCTSS | |
| SCHEMBL5202988 | 0.73 | DPP4 (0.59) | CTSKCTSLCTSBCTSS | |
| SCHEMBL19981817 | 0.73 | CTSK (0.57) | CTSKCTSLCTSBCTSSELANE | |
| SCHEMBL5203233 | 0.73 | PIN1 (0.54) | CTSKCTSLCTSBCTSSELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071454-A2 | SUBSTITUTED AZETIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS INC. (US) | 2004-08-26 | — | — | WO | disclosed |